The triangular relationship
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Diet – gut microbiota – inflammation
There is increasing evidence that our gut bacteria (microbiota) play a significant role in inflammation, a key driver of many chronic diseases. This review examined the impact of three dietary patterns on the microbiota and how that influences inflammation and overall health. A Western diet – high in processed foods, red meat, sugars and unhealthy fats – was found to encourage the growth of harmful bacteria, which increase the risk of inflammation obesity, diabetes, inflammatory bowel disease and cardiovascular disease.
In contrast, the Mediterranean diet, rich in fruits, vegetables, wholegrains, nuts and olive oil, supports a diverse microbiota, promoting anti-inflammatory effects and better health outcomes. Similarly, plant-based diets, abundant in fibre, polyphenols and plant proteins, boost the population of beneficial bacteria and promote the production of anti-inflammatory compounds while reducing harmful species.
The authors suggest that a further understanding of the connection between diet, gut microbiota and inflammation could be key to preventing and managing chronic diseases.
Randeni N, Bordiga M and Xu B. 2024 A comprehensive review of the triangular relationship among diet-gut microbiota-inflammation. International Journal of Molecular Sciences. 25 (17) 9,366.